Second Glance by Jodi Picoult
I've decided that I like Picoult's early novels best. They don't seem to be unbearably depressing like some of her more recent novels have been.
I enjoyed Second Glance very much. I liked how Picoult focused on the eugenics movement and drew comparisons to modern gene therapy.* I also liked the supernatural elements in the novel and how they were used to tie the past to the present. I thought the twist at the end was particularly satisfying.
* maybe gene therapy isn't the right term, but the right term is escaping me right now